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Liver Disease Management
Liver Disease Management is specialist medical care that diagnoses, monitors, and treats the full spectrum of liver conditions -- from fatty liver disease and viral hepatitis to cirrhosis -- protecting liver function, preventing complications, and optimising long-term outcomes through evidence-based treatment.
Overview
Key Benefits
Discover the advantages of choosing our liver disease management services.
HCV cure with DAA therapy prevents cirrhosis progression and reduces HCC risk
NAFLD lifestyle intervention can reverse early fibrosis with sustained weight loss
Beta-blocker prophylaxis reduces the risk of variceal haemorrhage by 40%
Early HCC detection by surveillance achieves curative resection or ablation in most cases
Complete alcohol abstinence in ARLD improves 5-year survival from below 50% to above 80%
Clinical Features
The technology, techniques and clinical approach behind our liver disease management.
FibroScan provides non-invasive liver stiffness measurement replacing liver biopsy for most staging
HCV DAA therapy achieves over 95% cure rate with 8 to 12 weeks of treatment
Variceal screening with beta-blocker prophylaxis prevents life-threatening first bleeds
6-monthly HCC surveillance in all cirrhotic patients detects cancer when curative treatment is possible
Abstinence from alcohol even in advanced cirrhosis significantly improves survival
Preparation Instructions
Complete abstinence from alcohol is the single most important intervention for alcohol-related liver disease. Attend all scheduled hepatocellular carcinoma surveillance ultrasounds at 6-monthly intervals if you have cirrhosis. NSAIDs are absolutely contraindicated in liver disease. Contact your hepatology team immediately for sudden abdominal swelling, confusion, fever, or vomiting blood.
The Procedure
Step-by-step guide to what you can expect during your liver disease management procedure.
Liver Function Test and Fibrosis Assessment
ALT AST GGT bilirubin albumin and INR are reviewed. Non-invasive fibrosis markers (FIB-4 score) and FibroScan elastography quantify liver stiffness as a surrogate of fibrosis stage -- guiding the urgency of further investigation and treatment.
Aetiology Identification
Hepatitis serology (HBsAg anti-HCV) autoimmune markers (ANA ASMA IgG) iron studies and caeruloplasmin identify the specific cause. Alcohol history is taken honestly and quantified. Metabolic risk factors (BMI diabetes dyslipidaemia) are assessed.
Hepatitis C Direct-Acting Antiviral Therapy
HCV genotype and treatment history guide DAA regimen selection. Glecaprevir/pibrentasvir or sofosbuvir/velpatasvir achieve SVR12 in over 95% of patients in 8 to 12 weeks. SVR12 (undetectable HCV RNA 12 weeks after treatment) confirms virological cure.
NAFLD Lifestyle Intervention
Weight loss of 5 to 10% body weight improves hepatic steatosis in NAFLD. Weight loss of above 10% can reverse NASH and early fibrosis. Structured dietary intervention and exercise prescription are coordinated with dietitian input.
Portal Hypertension Complication Management
Upper GI endoscopy screens for oesophageal varices in cirrhosis. Non-selective beta-blocker prophylaxis reduces first bleed risk from varices. Ascites is managed with sodium restriction and diuretics. Spontaneous bacterial peritonitis is treated with IV antibiotics.
Hepatocellular Carcinoma Surveillance
Six-monthly liver ultrasound and AFP in all cirrhotic patients detects HCC at an early treatable stage. Suspicious lesions are confirmed with contrast CT or MRI using LI-RADS criteria before treatment decision.
What to Expect
Your hepatologist reviews liver function tests, hepatitis serology, autoimmune markers, and imaging. Fibroscan quantifies liver stiffness as a non-invasive measure of fibrosis. Endoscopy is arranged for variceal screening in confirmed cirrhosis. Treatment decisions including antiviral therapy or lifestyle intervention are explained with expected response timelines and monitoring programmes.
Frequently Asked Questions
Common questions about liver disease management.
Related Services
Explore other services in our General Medicine department.
Hypertension Management
Diabetes Mellitus Management
Anaemia Investigation and Management
Ready to Get Started?
Schedule your consultation today and take the first step towards better health.
